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Dermatological Treatment Pharmaceutical Raw Materials Tacrolimus CAS 109581-93-3
Product Details:
Payment & Shipping Terms:
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Detailed Product Description
| CAS: | 104987-11-3 | State: | Solid |
|---|---|---|---|
| Mf: | C44h69no12 | MW: | 804.02 |
| Grade: | Pharmaceutical Grade | Appearance: | White To Light Yellow Crystal Powder |
| High Light: | Medication Steroids,Medicine Intermediate |
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Dermatological Treatment Pharmaceutical Raw Materials Tacrolimus CAS 109581-93-3
Quick Detail:
| Product Name | Tacrolimus |
| Alias | Tsukubaenolide Hydrate |
| CAS | 109581-93-3 |
| MF | C44H69NO12 |
| MW | 804.02 |
| Grade | Pharmaceutical Grade |
| Appearance | White To Light Yellow Crystal Powder |
Interactions
Also like ciclosporin, it has a wide range of interactions, including that with grapefruit which increases plasma-tacrolimus concentration. Several of the newer classes of antifungals, especially of the azole class (fluconazole, posaconazole) also increase drug levels by competing for degradative enzymes.
Ulcerative colitis
In recent years, tacrolimus has been used to suppress the inflammation associated with ulcerative colitis (UC), a form of inflammatory bowel disease. Although almost exclusively used in trial cases only, tacrolimus has shown to be significantly effective in the suppression of outbreaks of UC.
Dermatological use
As an ointment, tacrolimus is used in the treatment of eczema, in particular atopic dermatitis. It suppresses inflammation in a similar way to steroids, and is equally as effective as a mid-potency steroid. An important advantage of tacrolimus is that, unlike steroids, it does not cause skin thinning (atrophy), or other steroid related side effects.
It is applied on the active lesions until they heal off, but may also be used continuously in low doses (twice a week), and applied to the thinner skin over the face and eyelids.[citation needed] Clinical trials of up to one year have been conducted. Recently it has also been used to treat segmental vitiligo in children, especially in areas on the face.
Also like ciclosporin, it has a wide range of interactions, including that with grapefruit which increases plasma-tacrolimus concentration. Several of the newer classes of antifungals, especially of the azole class (fluconazole, posaconazole) also increase drug levels by competing for degradative enzymes.
Ulcerative colitis
In recent years, tacrolimus has been used to suppress the inflammation associated with ulcerative colitis (UC), a form of inflammatory bowel disease. Although almost exclusively used in trial cases only, tacrolimus has shown to be significantly effective in the suppression of outbreaks of UC.
Dermatological use
As an ointment, tacrolimus is used in the treatment of eczema, in particular atopic dermatitis. It suppresses inflammation in a similar way to steroids, and is equally as effective as a mid-potency steroid. An important advantage of tacrolimus is that, unlike steroids, it does not cause skin thinning (atrophy), or other steroid related side effects.
It is applied on the active lesions until they heal off, but may also be used continuously in low doses (twice a week), and applied to the thinner skin over the face and eyelids.[citation needed] Clinical trials of up to one year have been conducted. Recently it has also been used to treat segmental vitiligo in children, especially in areas on the face.
Delivery:
Orders are shipped everyday from Monday to Saturday. We take delivery very seriously and we do everything what we can so your order reach your doorstep safely. Please understand we can't ship during holidays.
Note: Please, don't ask us when your order gonna be shipped. We're doing our best and every paid order is our priority. You will be notified once your order is shipped.
So how long does it take for order to reach me? After you receive email " Your order has been shipped " from experience it takes about 7-20 days.
Delivery cost? It depends on your cart price. Shipping price will be displayed in your cart - after you add all products you need simply check your shopping cart.
What about discretion? No worries about that. There will be no company name or steroid related words. We take it very seriously and we respect your privacy. Nooone will ever know what's inside the parcel. Only we and you.
What about delivery success rate to you? Our experience says 99%. We know what we're doing that is why we're the best.
Do you offer tracking code? Yes, we do.
Please, do care about your parcel and if order doesn't come within 20 days, contact us immediately so we can help.
Orders are shipped everyday from Monday to Saturday. We take delivery very seriously and we do everything what we can so your order reach your doorstep safely. Please understand we can't ship during holidays.
Note: Please, don't ask us when your order gonna be shipped. We're doing our best and every paid order is our priority. You will be notified once your order is shipped.
So how long does it take for order to reach me? After you receive email " Your order has been shipped " from experience it takes about 7-20 days.
Delivery cost? It depends on your cart price. Shipping price will be displayed in your cart - after you add all products you need simply check your shopping cart.
What about discretion? No worries about that. There will be no company name or steroid related words. We take it very seriously and we respect your privacy. Nooone will ever know what's inside the parcel. Only we and you.
What about delivery success rate to you? Our experience says 99%. We know what we're doing that is why we're the best.
Do you offer tracking code? Yes, we do.
Please, do care about your parcel and if order doesn't come within 20 days, contact us immediately so we can help.
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