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CAS 13647-35-3 Pharmaceutical Raw Materials Trilostane Anti Tumor Drugs
Detailed Product Description
Product Name: |
Trilostane |
Alias: |
TRILOSTANE |
CAS NO: |
13647-35-3 |
Purity: |
99% |
Apperance: |
white crystalline powder |
Application: |
Pharmaceutical intermediates |
Quick Detail:
1. Trilostane
2. CAS No.: 13647-35-3
3. Purity: 98.5%min
4. Other Names: 4a,5a,17b)-3,17-Dihydroxy-4,5-epox...
5. MF: C20H27NO3
6. EINECS No.: 237-133-0
7. Appearance: White to off-white power
8. Type: Antineoplastic Agents
9. Grade Standard: Medicine Grade
10. Manufacturer :QuanAo
11.. Packing: As customers requirments
12: Usage: Anti-tumor drugs and immunosuppressants
Description:
Trilostane is an inhibitor of 3 β-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome.
It was withdrawn from human use in the United States market in April 1994.[3][4] The drug is available in the United Kingdom for use in humans under the brand name Modrenal and is used for treatment of Cushing's disease and for breast cancer treatment
.
Applications:
Albuterol Sulfate/Salbutamol/Ventolin powders/Proventil powders/CAS No: 51022-70-9
It is usually given by the inhaled route for direct effect on bronchial smooth muscle. This is usually achieved through a metered dose inhaler (MDI), nebulizer or other proprietary delivery devices (e.g. Rotahaler or Autohaler). In these forms of delivery, the maximal effect of salbutamol can take place within five to 20 minutes of dosing, though some relief is immediately seen. It can also be given intravenously.
Used in the treatment of bronchial asthma, asthmatic bronchitis, emphysema, patients bronchospasm.
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Specifications(coa and hplc):
Test Items |
Specification |
Test Results |
|
Appearance |
white oralmost white,crystalline powder |
Conform |
|
Solubility |
Freely soluble in water,practically insoluble or very slightly soluble in alcohol and in methylene chloride. |
Conform |
|
Identification |
A |
The UV absorption spectrum of the sample shows an absorption maximum at 276nm.The specific absorbance at the Maximum is55 to 64. |
Conform |
B |
Infraed absorption spectrophotometry. |
Conform |
|
C |
Chromatogram obtained with test solution (b) is similar in position color & size to the principal spot in the chromatogram obtained with the reference solution. |
Conform |
|
D |
An orange-red color develop in methylene chloride layer. |
Conform |
|
E |
It geves reaction (a) of sulphates. |
Conform |
|
Appearance of solution |
Solution S is clear and not more intensely coloured than reference solution in BY6. |
Conform |
|
Optical rotation |
negative 0.10° to +0.10°determined on solution S. |
+0.01° |
|
Acidity or alkalinity |
NMT 0.4ml of 0.01M HCL is required to change the color of the indicator to red. |
Conform |
|
Related substances |
Impurity J ≤0.20% |
Conform |
|
Any other impurity ≤0.30% |
Conform |
||
Total impurity ≤1.0% |
Conform |
||
Boron |
≤50ppm |
Conform |
|
Sulphated ash |
≤0.10% |
0.06% |
|
Loss on drying |
≤0.5% |
0.30% |
|
Assay(on dried basis) |
98.0~101.0% |
99.5% |
|
Conclusion |
The test results above BP2009 |
Competitive Advantage:
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2. well experienced in delivering the parcels to you.
3. Full stock ensures prompt delivery.
4. Superior after-sales service.
5. Package will be reshipped if sent unseccessfully.
6. Experiential shopping .Besides raw steroid powder and liquid, we offer steroid solutions and recipes.
We can teach you how to make steroid solutions on the site. Any visit to our lab is welcomed.
Keywords :
Salbutamol ;
Lower blood testosterone levels, inhibiting its synthesis
Treatment of cushing's syndrome
Pharmaceutical intermediates;
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