1. Basic Info

Product Name:	ETIZOLAM
Synonyms:	ETIZOLAM;4-(2-Chlorophenyl)-2-ethyl-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine;4-(o-Chlorophenyl)-2-ethyl-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine;Y-7131;4-(o-Chlorophenyl)-2-ethyl-9-methyl-6H-thieno(3,2-F)-S-triazolo(4,3-A)(1,4)diazepine;4H-S-Triazolo(3,4-C)thieno(2,3-E)(1,4)-diazepine, 6-(o-chlorophenyl)-8-ethyl-1-methyl-;6-(o-Chlorophenyl)-8-ethyl-1-methyl-4H-S-triazolo(3,4-C)thieno(2,3-E)(1,4)-diazepine;6-(o-Chlorphenyl)-8-aethyl-1-methyl-4H-S-triazolo(3,4-C)thieno(2,3-E)(1,4)diazepin
CAS:	40054-69-1
MF:	C17H15ClN4S
MW:	342.85
EINECS:	662-368-4
Product Categories:	Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Inhibitors;-;intermediate-;pharmaceutical intermediate;pharmaceutical intermediate and medicine grade
Mol File:	40054-69-1.mol

2. Descriptions:

Etizolam is a benzodiazepine analog used for the short-term treatment of insomnia, anxiety or panic attacks. It has amnesic, anxiolytic, anticonvulsant, and hypnotic, sedative and skeletal muscle relaxant properties. It acts on the benzodiazepine site of the GABA-A receptor as an agonist to increase inhibitory GABAergic transmission throughout the central nervous system.

Savoldi, F, G. Somenzini, and U. Ecari. "Etizolam versus placebo in the treatment of panic disorder with agoraphobia: a double-blind study."Current Medical Research & Opinion 12.3(1990):185.
Hirashima, Y, et al. "Etizolam, an anti-anxiety agent, attenuates recurrence of chronic subdural hematoma--evaluation by computed tomography." Neurologia medico-chirurgica 42.2(2002):53-55

Etizolam is a potent thienodiazepine anxiolytic closely related to brotizolam. Pharmacologically, however, its profile most resembles that of diazepam.

3. Applications:

Etilozam is a a thienodiazepine benzodiazepine derivative, and has amnesic, anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. Etizolam is an anxiolytic related to that of the classic benzodiazepines. Etizolam has effect on monoamine metabolism in brain. Etilozam can be used for the short-term treatment of insomnia, anxiety or panic attacks.

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