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|Molecular Formula:||C22H21Cl3N4O||Molecular Weight:||500.25|
|PH:||(10% Solution) 4-7||TLC:||Only One Spot|
|Melting Point:||230 ~ 240 Centigrade||Usage:||Rimonabant Is A Selective Antagonist Of CB1 With I|
Mifeprex Rimonabant Weight Loss CAS 168273-06-1 Treat Obesity Smoking Cessation
Molecular formula: C22H21Cl3N4O.
Molecular weight: 500.25
Formulation: White or almost white crystalline powder
Purity: ≥ 99% by HPLC
Appearance White crystalline powder
Package 1kg/aluminium foil bag or as required
Rimonabant has also been shown to be a μ-opioid receptor antagonist (possibly the contributing factor in its reported dysphoric qualities).Its main effect is reduction in appetite.
In a 2006 (2 year) study reported in JAMA, "Compared with the placebo group, the 20 mg of rimonabant group produced greater mean (SEM) reductions in weight (-6.3 [0.2] kg vs -1.6 [0.2] kg; P<.001), waist circumference (-6.1 [0.2] cm vs -2.5 [0.3] cm; P<.001), and level of triglycerides (percentage change, -5.3 [1.2] vs 7.9 [2.0]; P<.001) and a greater increase in level of high-density lipoprotein cholesterol (percentage change, 12.6 [0.5] vs 5.4 [0.7]; P<.001)."
Rimonabant may also be found to be effective in assisting some smokers to quit smoking. Sanofi is currently conducting studies to determine the possible value of rimonabant in smoking-cessation therapy. The Studies with Rimonabant and Tobacco Use (STRATUS) program involves more than 6,000 subjects. STRATUS is designed to explore two smoking-related therapies: first, to use rimonabant directly to aid in smoking cessation; second, to help prevent weight gain in former smokers. Initial results apparently suggest rimonabant is effective for both uses. However, the FDA has explicitly stated to Sanofi that, without additional studies, rimonabant cannot be approved in the United States for smoking cessation therapy. According to a Cochrane Collaboration review in 2007, rimonabant "may increase the odds of quitting approximately 11/2-fold".
An experimental wonder drug, Rimonabant, helps you lose weight, quit smoking and it also helps protect your heart. Trials have shown that 33% of people on Rimonabant lost 10% of body weight and kept their weight down for two years - this is a record, no other diet drug has managed to keep a person's weight down for so long. As well as keeping you lean, the drug also helps you quit the smoking habit. This will be of great interest for many smokers who are afraid to give up because they say they will put on loads of weight if they do (young female smokers worry about this the most).
Rimonabant / Acomplia selectively blocks the CB1 receptors that are present in the brain and other peripheral organs important in fat/lipid and glucose metabolism, including muscle, gastrointestinal tract, liver and adipose tissue. Basically, it switches off those brain circuits that are responsible for making people hungry while smoking .Acomplia, along with CB1 receptors, reduces the EC system's over-activity.
Rimonabant / Acomplia is said to have reduced the overall body fat by 10% in one out of three users. Also, it is reported that those users did not gain back more than a kilo over the next two years if the patients remained on Rimonabant. Rimonabant was recommended for those with a BMI of 30 or greater, who were considered obese, and is most successful when combined with exercise and a proper diet.
|roduct Name||Rimonabant||Batch No.||150728|
|Test Items||Specification||Test Results|
|Appearance||Off white crystalline powder||Off white crystalline powder|
|Solubility||Conforms||Freely soluble in methanol|
|T.L.C.||Only one spot||Only one spot|
|1||High quality and good price.|
|2||Delivery in time.|
|3||100% customs pass guaranteed.|
|4||Good after-sale service. Solve your problems in time.|