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|Product Name:||Cjc-1295 Without Dac||CAS:||863288-34-0|
|Purity:||> 98.0%||Appearance:||White Powder|
|Related Substance:||Total Impurities(%) < 2.0%||Acetate Content:||< 15.0%|
|Bacterial Endotoxins:||<5 IU/mg||Skype:||Trustful_3|
Cjc-1295 Without Dac
|Product name||Cjc-1295 Without Dac|
|Related substance||Total Impurities(%) < 2.0%|
|Acetate content||< 15.0%|
|Bacterial Endotoxins||< 15.0%|
|Bacterial Endotoxins||<5 IU/mg|
Cjc-1295 Peptide Chain: Tyr-d-ALA-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-
CJC-1295 DAC vs. CJC-1295 No DAC
Is identical but the difference between the two peptides are the span of the half-life. Modified GRF 1-
29 and Sermorelin have a very short acting half-life of about 30 minutes, while CJC-1295 DAC has a half-
life that can last up to approximately 8 days. Many a scientist have reported that the short half-
life of Sermorelin and Modified GRF 1-
29 is considered to be much more natural as they produce a short pulse.
What is CJC-1295 without DAC and used for?
Modified GRF 1-29 is also known as Mod GRF 1-29, but even more commonly known as CJC-
1295 without DAC. It is a protein that is 29 amino acids long and it is a GHRH analogue. CJC-
1295 without DAC acts on receptors at the pituitary gland to stimulate the release of Human Growth
CJC 1295 without DAC could be referred to more properly as a second generation derivative of GHRH. GHRH
is modified to create what is known as Releasing Factor (GRF) 1-29, also known as Sermorelin. GRF 1-
29 is then further modified to create Mod GRF 1-29 which is CJC-1295 without DAC.
Application & More information for CJC-1295 without DAC
Releasing Hormone (GHRH), which is the endogenously secreted GHRH by the arcuate nucleus of the
hypothalamus of the human body, is 44 amino acids long. It was discovered, however, that only the first
29 amino acids of the protein were equally as effective in binding to receptors on the pituitary gland as the full 44 amino acid structure. The first 29 amino acids in its protein structure were then isolated, which wasthen called GRF 1-29, but the problem with this derivative of GHRH was the fact that it was rapidly metabolized and cleared from the body by enzymes. Studies have reported that GRF 1-29's half-
life is less than 10 minutes and as little as 5 minutes. This was obviously not enough time to ensure a
maximized and sustained release ofHGH from the pituitary gland, as studies have demonstrated that the full potential of an HGH pulse from the pituitary requires at least 30 minutes as evidenced by the fact that much higher HGH levels (50 times greater) were observed 15 - 30 minutes into subcutaneous
administration of GHRH analogues.Therefore, the solution to this was to modify GRF 1-29 by replacing various amino acids in its structure with other amino acids that would provide a greater
resistance to breakdown and cleavage by enzymes. There were many modified analogues developed,
and Mod GRF 1-29 (CJC-1295 without DAC) was eventually selected for use, which demonstrated the most promising effects.Mod GRF 1-29 is a modification of GRF 1-29, specifically at amino acids #2, #8, #15, and #27. The result is an extended half-life to that of at least 30 minutes.Mod GRF 1-29 acts upon receptors located in the anterior pituitary gland, and signals the pituitary gland to increase Human production and cause a release of massive quantities of Human Hormone in a pulsatile manner. The effects of Mod GRF 1-29 are very similar from what would be expected from synthetic HGH administration over the long term,although the amount of time that the released human growth hormone will remain in circulation is of a farless amount of time than synthetic Human Growth Hormone does. Therefore, multiple applications of Mod GRF 1-29 is recommended throughout the day in order tosimulate Human Growth Hormone levels that remain high on a constant basis. Mod GRF 1-29 (CJC-
1295 without DAC) is commonly combined with a Ghrelin mimetic (also known as a GHRP - Releasing
Hexapeptide), such as GHRP-6, GHRP-2, Hexarelin, or Ipamorelin in order to initiate and amplify a greater pulse from the pituitary compared to Mod GRF 1-29 used solitarily on its own.
T-A002 PEG MGF
T-A003 CJC-1295 with DAC
T-A004 CJC-1295 without DAC
T-A015 pentadecapeptide BPC 157
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