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PT 141 Bremelanotide 10Mg Human Growth Hormone Peptide Powder CAS 32780-32-8

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PT 141 Bremelanotide 10Mg Human Growth Hormone Peptide Powder CAS 32780-32-8

China PT 141 Bremelanotide 10Mg Human Growth Hormone Peptide Powder CAS 32780-32-8 supplier
PT 141 Bremelanotide 10Mg Human Growth Hormone Peptide Powder CAS 32780-32-8 supplier PT 141 Bremelanotide 10Mg Human Growth Hormone Peptide Powder CAS 32780-32-8 supplier

Large Image :  PT 141 Bremelanotide 10Mg Human Growth Hormone Peptide Powder CAS 32780-32-8

Product Details:

Place of Origin: China
Brand Name: YIHAN
Certification: ISO,GMP,KOSHER
Model Number: PT-141

Payment & Shipping Terms:

Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: safe and Professional Disguised Package
Delivery Time: Within 24 hours After Payment
Payment Terms: T/T , Western Union , bank transfer , MoneyGram
Supply Ability: 500Ton/Month
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Detailed Product Description
CAS: 32780-32-8 Bremelanotide: PT-141
Cas No: 32780-32-8 Molecular Formula: C50H68N14O10
Molecular Weight: 1025.2 Purity (HPLC): 98.0%min.
Amino Acid Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH Synonyms: Bremelanotide, PT-141 Acetate

PT 141 Bremelanotide 10Mg Human Growth Hormone Peptide Powder CAS 32780-32-8

 

Quick Details

CAS No.: 32780-32-8 Other Names: PT 141 MF: C7H15NO4
EINECS No.: 258279-04-8 Place of Origin: ShangHai, China (Mainland) Type: Auxiliaries and Other Medicinal Chemicals
Grade Standard: Medicine Grade Usage: Animal Pharmaceuticals, Bodybuilding    
Model Number:   Purity: 99%min Product Name: PT141
Appearance: Powder Grade: Medical Standard: USP Grade
Colour: White Export Markets: Global Production Capacity: 10000g
   


Description
PT-141 (Bremelanotide) is a highly potent synthetic peptide analogue of α-MSH that may elicit aphrodisiac effects through stimulation of melanocortin receptors. PT-141 (Bremelanotide) consists of seven amino acids and is a cyclic, shortened lactam variant of alpha-Melanocyte-stimulating hormone (α-MSH), a multifunctional peptide that regulates a broad array of physiological functions. In studies, bremelanotide was shown to induce lordosis in an animal model and was also effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder).

Specification
Name: PT-141
Synonyms: Bremelanotide, PT-141 Acetate
CAS #: 189691-06-3
Molecular Formula: C50H68N14O10
Molecular Mass: 1025.2 Da (g/mol)
Amino Acid Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH


Purity
PT-141 has a peptide purity level that exceeds 99.0% as determined by HPLC and MS. This peptide was synthesized with no additives and is supplied as a white lyophilized (freeze-dried) powder.


Usage
Bremelanotide, similarly to its analogues α-MSH and melanotan II, acts as a non-selective agonist of all of the melanocortin receptors except MC2, where it lacks significant affinity. Reported activity of the drug is as follows:
MC1 (Ki = 0.68 nM)
MC2 (Ki > 1000 nM)
MC3 (Ki = 72.07 nM)
MC4 (Ki = 19.25 nM)
MC5 (Ki = 166.8 nM)

Bremelanotide appears to stimulate sexual desire and arousal completely or mostly via activation of the MC4 receptor (the MC3 receptor may also be involved). It modulates inflammation and limits ischemia via activation of the MC1 and MC4 receptors.

According to Palatin Technologies' original 2003 patent for bremelanotide, it possesses approximately 50 times the potency of melanotan II as an inducer of erection in male rats. In addition, it was stated in the patent that the therapeutic window of bremelanotide in animals (specifically, the range of induction of the desired sexual arousal relative to the induction of side effects including nausea, yawning, stretching, and decreased appetite) was >1,000-fold, whereas that of melanotan II was only 3- to 4-fold. They concluded that bremelanotide would be more tolerable than melanotan II.

PT 141 Bremelanotide 10Mg Human Growth Hormone Peptide Powder CAS 32780-32-8

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