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Toremifene Citrate Anti Estrogen Steroids CAS 89778-27-8 For Cancer Treatment

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Toremifene Citrate Anti Estrogen Steroids CAS 89778-27-8 For Cancer Treatment

China Toremifene Citrate Anti Estrogen Steroids CAS 89778-27-8 For Cancer Treatment supplier
Toremifene Citrate Anti Estrogen Steroids CAS 89778-27-8 For Cancer Treatment supplier Toremifene Citrate Anti Estrogen Steroids CAS 89778-27-8 For Cancer Treatment supplier

Large Image :  Toremifene Citrate Anti Estrogen Steroids CAS 89778-27-8 For Cancer Treatment

Product Details:

Place of Origin: China
Brand Name: YIHAN
Certification: ISO9001,USP
Model Number: Toremifene Citrate

Payment & Shipping Terms:

Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: foil bag or tin
Delivery Time: Within 24 hours after receiving the payment
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 5000kg/month
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Detailed Product Description
Color: White Purity: 99% Min.
CAS: 89778-27-8 Appearance: Powder
Einecs: N/a Molecular Weight: 598.08
Molecular Formula: C32h36clno8 State: Solid

Toremifene Citrate Anti Estrogen Steroids CAS 89778-27-8 For Cancer Treatment

 

Quick Detail:

 

Toremifene Citrate

Cheap Price Manufacturer Supply Toremifene Citrate 89778-27-8

Synonyms: FC 1157a; Fareston; NK 622; NSC 613680
CAS: 89778-27-8 
Molecular Formula:  C26H28ClNO·C6H8O7
Molecular Weight: 598.09

Melting Point:  158-164 ºC 
Boiling Point:  535.1 ºC at 760 mmHg 
Density: 1.045g/cm3  
Refractive index: 1,416-1,418 
Appearance: White or almost white powder 

 

Description:

is a member of a category, family, and class of drugs that are known as SERMs (Selective Estrogen Receptor Modulators). SERMs fall under an even broader category of drugs that are known as anti-estrogens, and the cousin family of SERMs (that also fall under anti-estrogens) are aromatase inhibitors, commonly abbreviated as AIs. SERMs include compounds such as Nolvadex and Clomid (Clomiphene Citrate). Aromatase inhibitors (AIs) include compounds such as Arimidex ) Aromasin, (Femara). Although the two fall under the category of anti-estrogens, they are both sub-categories that branch off into their own families, as SERMs and AIs differ greatly in their mechanism of action within the human body concerning how they control or block Estrogen. There has been much misunderstanding and misconception in previous decades as to what each of these do, and this should always be first clarified to the reader before describing Toremifene.

Applications:

Toremifene citrate is an oral selective estrogen receptor modulator (SERM) which helps oppose the actions of estrogen in the body. Licensed in the United States under the brand name Fareston, toremifene citrate is FDA-approved for use in advanced (metastatic) breast cancer. It is also being evaluated for prevention of prostate cancer under the brand name Acapodene.

It has already been covered that Toremifene is a SERM, and serves to block Estrogen at various receptor sites in certain tissues within the body (breast tissue in particular). As a layman explanation, Toremifene pretends to be a 'fake' Estrogen that occupies Estrogen receptors within breast tissue. With these receptors occupied by Toremifene, real Estrogen cannot perform their jobs there.

Toremifene does not reduce total blood plasma levels of Estrogen. In addition to being antagonistic to Estrogen receptors in breast tissue, it is also antagonistic to Estrogen at the hypothalamus gland (this essentially 'tricks' the hypothalamus into thinking there is little or no circulating Estrogen levels in the body, causing it to increase its manufacture of Testosterone so that it can utilize aromatization to restore these levels.

Toremifene is also agonistic to Estrogen receptors in other tissues in the body (within the liver in particular). This means that whileToremifene will act as an anti-estrogen in breast tissue and the hypothalamus, it will act as an Estrogen within the liver. This can have beneficial impacts especially during an anabolic steroid cycle, such as improving and shifting cholesterol levels into a more favorable range.


Specification:

COA:


Test items
Quality requirements Results
Description White or like white crystalline powder White crystalline powder
Solubility Freely soluble in pyridine and acetic acid(100), sparingly soluble in methanol, slightly soluble in ethanol, very slightly soluble in water, and practically insoluble in diethyl ether Freely soluble in pyridine and acetic acid(100), sparingly soluble in methanol, slightly soluble in ethanol, very slightly soluble in water, and practically insoluble in diethyl ether
Melting point 159~163ºC 159.0~160.5ºC
Identification    
(a)Positive reaction Must comply Complies
(b)Positive reaction Must comply Complies
(c) UV There is the strongest absorption at the wavelength of 234~238nm and 275~278nm. There is the strongest absorption at the wavelength of 236.8nm and 276.2nm.
(d) IR There is absorption at 1741, 1703, 1585, 1241 and 706cm-1 . There is absorption at 1741, 1703, 1585, 1241 and 706cm-1 .
Purity 99%  
(a) Relative substances    
E-isomer ≤0.5% 0.001%
Total relative substances ≤1.0% 01%
(b)Heavy metals ≤10ppm <10ppm
Loss on drying ≤1.0% 0.1%
  ≤0.089% 0.0002%
Ethanol ≤0.5% 0
Acetone ≤0.5% 0.21%
  ≤0.072% 0.0001%
Chlorobenzen ≤0.036% 0
Benzene ≤0.0002% 0
Residue on ignition ≤0.1% 0.04%
Assay ≥98.5% (Calculated by C26H28ClNO .C6H8O7) 99.7%
Conclusion: The results comply with the requirements of the export standard.
 

Toremifene Citrate Anti Estrogen Steroids CAS 89778-27-8 For Cancer Treatment

Semi-finished Injectable / Oral steroids:


Test prop-----------100mg/ml 200mg/ml
Test enan-----------250mg/ml 300mg/ml 400mg/ml 500mg/ml 600mg/ml
Test cyp------------200mg/ml 250mg/ml 300mg/ml
Test Sustanon-------200mg/ml 250mg/ml 300mg/ml 400mg/ml
Deca----------------200mg/ml 250mg/ml
Equipoise-----------200mg/ml 300mg/ml
Tren ace------------100mg/ml 200mg/ml
Tren enan-----------100mg/ml 200mg/ml
Dianabol------------50mg/ml
Winstrol------------50mg/ml
Masteron------------100mg/ml 150mg/ml
Primobolone---------100mg/ml
Supertest-----------450mg/ml
Anomass ------------400mg/ml
Ripex---------------225mg/ml
Tritren-------------180mg/ml
Tri Test------------300mg/ml
Tri Deca------------300mg/ml
Test Blend----------450mg/ml 500mg/ml
Nandro Test---------225mg/ml
Mass----------------500mg/ml
Cut Depot-----------400mg/ml
Tren Test-----------225mg/ml
Nandro Test Depot---------450mg/ml
Equi Test-----------------450mg/ml
Rip Cut-------------------175mg/ml
Tren Test Depot-----------450mg/ml

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