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CAS 96-48-0 Pharmaceutical Intermediates 100% Safe GBL Gamma Butyrolactone

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CAS 96-48-0 Pharmaceutical Intermediates 100% Safe GBL Gamma Butyrolactone

China CAS 96-48-0 Pharmaceutical Intermediates 100% Safe GBL Gamma Butyrolactone supplier
CAS 96-48-0 Pharmaceutical Intermediates 100% Safe GBL Gamma Butyrolactone supplier CAS 96-48-0 Pharmaceutical Intermediates 100% Safe GBL Gamma Butyrolactone supplier

Large Image :  CAS 96-48-0 Pharmaceutical Intermediates 100% Safe GBL Gamma Butyrolactone

Product Details:

Place of Origin: China
Brand Name: YIHAN
Certification: GMP,USP,BP,ISO 9001
Model Number: 96-48-0

Payment & Shipping Terms:

Minimum Order Quantity: 1L
Price: USD80 +L
Packaging Details: Discreet Package or as Required.
Delivery Time: 3-5 work days
Payment Terms: MoneyGram,Paypal, T/T, Western Union
Supply Ability: 5000kg/Month
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Detailed Product Description
Product Name: Gbl CAS: 96-48-0
Type: Pharmaceutical Intermediate Appearance: Liquid Colorless
Purity: 99%

1. Basic Info

 

Product Name: Gamma-butyrolactone(GBL)
Synonyms: FEMA 3291;GAMMA-BUTYROLACTONE;GAMA-BUTYROLACTONE;GAMMA-HYDROXYBUTYRIC ACID LACTONE;GBL;GBL-EL;G-BUTYROLACTONE;endo-cis-5-norbornene-endo-2,3-dicarboxylic anhydride
CAS: 96-48-0
MF: C4H6O2
MW: 86.09
EINECS: 202-509-5
Product Categories: organic interme-;Pharmaceutical Intermediates;-;Heterocycles;Miscellaneous Reagents;Halogenated Heterocycles ,Thiophenes ,Thiazolines/Thiazolidines
Mol File: 96-48-0.mol
Gamma-butyrolactone(GBL) Structure

 

 

 

2. Descriptions:

 

amma-Butyrolactone (γ-butyrolactone or GBL) is a hygroscopic colorless liquid with a weak characteristic odor which is soluble in water. GBL is a common solvent and reagent in chemistry as well as being used as a flavouring, as a cleaning solvent, as a superglue remover, and as a solvent in some wet aluminium electrolytic capacitors. In humans it acts as a prodrug for GHB, and it is used as a recreational intoxicant with effects similar to alcohol.
GBL has been found in extracts from samples of unadulterated wines. This finding indicates that GBL is a naturally occurring component in some wines and may be present in similar products. The concentration detected was approximately 5 μg/mL and was easily observed using a simple extraction technique followed by GC/MS analysis. GBL can be found in cheese flavourings but typically results in a content of 0.0002% GBL in the final foodstuff.
GBL is a lactone. It is hydrolyzed under basic conditions, for example in a sodium hydroxide solution into sodium gamma-hydroxybutyrate, the sodium salt of gamma-hydroxybutyric acid. Under acidic conditions it forms an equilibrium mixture of both compounds. These compounds then may go on to form a polymer. When treated with a non-nucleophilic base, like lithium diisopropylamide, GBL can become an alpha-carbon nucleophile. The related compound caprolactone can be used to make a polyester in this manner.
GBL is not active in its own right; its mechanism of action stems from its identity as a prodrug of GHB. The hypnotic effect of GHB is enhanced by combination with alcohol. A 2003 rat study showed that GBL in combination with ethanol showed a potentiated hypnotic effect, as the sleep-timing measure was longer than both of the individual components combined.

 

 

 

3. Applications:

 

GBL is an important chemical raw material and intermediate for medicine, and also the intermediate of the synthesize N-methyl pyrrolidone, α -pyrrolidone, polyvinyl pyrrolidone, α -acetyl-γ -butyrolactone, methionine and the butyric acid compounds. This product features a strong solubility, and is a good solvent for polyacrylonitrile, epoxy resin, polyvinyl butyral, polyvinyl chloride and its copolymers, and cellulose polymers. In medical industry, it is mainly used in synthesizing cyclopropylamine, etc.

 

 

pecificatiuon:


Check Item
Standard Value Results
Appearance Transparent liquid Transparent liquid
Purity (wt%,GC) ≥99.80 99.92%
Moisture (wt%,K.F.) ≤0.03 0.02
Color (Hazen) ≤20 5
Density (D,g/ml) 1.125~1.130 1.126
Refractivity) 1.436~1.437 1.4367
Glycol (wt%,GC) ≤0.02 0.003
Tetrahydrofuran (wt%,GC) ≤0.03 0.024
 

 

 

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About us:


we, Yihan Industrial Co., Ltd from china are specilized in steroids powder , semi-finished liquids , peptides , Sarm powder,HGH,HCG,Finished Liquid and other pharmaceutical materials for many years .

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