Payment & Shipping Terms:
|Type:||Pharmaceutical Intermediate||Appearance:||Liquid Colorless|
|Synonyms:||FEMA 3291;GAMMA-BUTYROLACTONE;GAMA-BUTYROLACTONE;GAMMA-HYDROXYBUTYRIC ACID LACTONE;GBL;GBL-EL;G-BUTYROLACTONE;endo-cis-5-norbornene-endo-2,3-dicarboxylic anhydride|
|Product Categories:||organic interme-;Pharmaceutical Intermediates;-;Heterocycles;Miscellaneous Reagents;Halogenated Heterocycles ,Thiophenes ,Thiazolines/Thiazolidines|
amma-Butyrolactone (γ-butyrolactone or GBL) is a hygroscopic colorless liquid with a weak characteristic odor which is soluble in water. GBL is a common solvent and reagent in chemistry as well as being used as a flavouring, as a cleaning solvent, as a superglue remover, and as a solvent in some wet aluminium electrolytic capacitors. In humans it acts as a prodrug for GHB, and it is used as a recreational intoxicant with effects similar to alcohol.
GBL has been found in extracts from samples of unadulterated wines. This finding indicates that GBL is a naturally occurring component in some wines and may be present in similar products. The concentration detected was approximately 5 μg/mL and was easily observed using a simple extraction technique followed by GC/MS analysis. GBL can be found in cheese flavourings but typically results in a content of 0.0002% GBL in the final foodstuff.
GBL is a lactone. It is hydrolyzed under basic conditions, for example in a sodium hydroxide solution into sodium gamma-hydroxybutyrate, the sodium salt of gamma-hydroxybutyric acid. Under acidic conditions it forms an equilibrium mixture of both compounds. These compounds then may go on to form a polymer. When treated with a non-nucleophilic base, like lithium diisopropylamide, GBL can become an alpha-carbon nucleophile. The related compound caprolactone can be used to make a polyester in this manner.
GBL is not active in its own right; its mechanism of action stems from its identity as a prodrug of GHB. The hypnotic effect of GHB is enhanced by combination with alcohol. A 2003 rat study showed that GBL in combination with ethanol showed a potentiated hypnotic effect, as the sleep-timing measure was longer than both of the individual components combined.
GBL is an important chemical raw material and intermediate for medicine, and also the intermediate of the synthesize N-methyl pyrrolidone, α -pyrrolidone, polyvinyl pyrrolidone, α -acetyl-γ -butyrolactone, methionine and the butyric acid compounds. This product features a strong solubility, and is a good solvent for polyacrylonitrile, epoxy resin, polyvinyl butyral, polyvinyl chloride and its copolymers, and cellulose polymers. In medical industry, it is mainly used in synthesizing cyclopropylamine, etc.
|Appearance||Transparent liquid||Transparent liquid|
Local Anesthetic Drugs we supply
|Procaine Base||CAS 59-46-1a|
|Lidocaine HCl||CAS 73-78-9|
|Lidocaine Hydrochloride||CAS 51-05-8|
|Xylocaine Lidocaine||CAS 137-58-6|
|Tetracaine HCl||CAS 136-47-0|
|Propitocaine Hydrochloride||CAS 1786-81-8|
|Aarticaine Hydrochloride||CAS 23964-57-0|
|Procaine Hydrochloride||CAS 51-05-8|
|Tetracaine hydrochloride||CAS 136-47-0|
|Lidocaine Base||CAS 137-58-6|
|Dyclonine hydrochloride||CAS 536-43-6|
|Tetracaine Base||CAS 94-24-6|
|Dibucaine Hydrochloride||CAS 61-12-1|
|Proparacaine Hydrochloride||CAS 5875-06-9|
|Ropivacaine Hydrochloride||CAS 98717-15-8|
|Bupivacaine Hydrochloride||CAS 14252-80-3|
we, Yihan Industrial Co., Ltd from china are specilized in steroids powder , semi-finished liquids , peptides , Sarm powder,HGH,HCG,Finished Liquid and other pharmaceutical materials for many years .
If you have any further questions or need a sample,Please do not hesitate to contact me.Thank you!