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CAS 112809-51-5 Letrozole / Femara Steroid Powders For Women Breast Cancer Treatment

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CAS 112809-51-5 Letrozole / Femara Steroid Powders For Women Breast Cancer Treatment

China CAS 112809-51-5 Letrozole / Femara Steroid Powders For Women Breast Cancer Treatment supplier
CAS 112809-51-5 Letrozole / Femara Steroid Powders For Women Breast Cancer Treatment supplier CAS 112809-51-5 Letrozole / Femara Steroid Powders For Women Breast Cancer Treatment supplier

Large Image :  CAS 112809-51-5 Letrozole / Femara Steroid Powders For Women Breast Cancer Treatment

Product Details:

Place of Origin: China
Brand Name: YIHAN
Certification: GMP,USP,BP,ISO 9001
Model Number: 112809-51-5

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: USD3-5 +g
Packaging Details: Discreet Package or as Required.
Delivery Time: 3-5 work days
Payment Terms: MoneyGram,Paypal, T/T, Western Union
Supply Ability: 5000kg/Month
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Detailed Product Description
Product Name: Letrozole Advantages: Reship Policy
Suitable For: Adult CAS: 112809-51-5
Type: Pharmaceutical Intermediate Appearance: White Powder
Application: Pharm Intermediates

1. Basic Info

 

Product Name: Letrozole
Synonyms: Aromatase Inhibitor II, Letrozole - CAS 112809-51-5 - Calbiochem;LetrozoleUsp28;Letrozole99%;CGS-20267, Femara;LETRAZOLE;letrozolex;4,4'-(1H-1,2,4-Triazol-1-ylmethylene)dibenzonitrile;4,4'-(1H-1,2,4-Triazole-1-ylmethylene)bisbenzonitrile
CAS: 112809-51-5
MF: C17H11N5
MW: 285.30274
EINECS: 675-034-8
Product Categories: -;Anti-Cancer;Pharmaceutical material and intermeidates;Active Pharmaceutical Ingredients;Letrozole;Antineoplastic;Pharmaceuticals;API's;APIs;Antibiotics;All Inhibitors;anti-neoplastic;Inhibitors;Intermediates & Fine Chemicals;Aromatics;Heterocycles;ELOXATIN;Anti-cancer&immunity
Mol File: 112809-51-5.mol
Letrozole Structure

 

 

2. Descriptions:

 

Letrozole is used to treat postmenopausal women with hormone receptor positive early breast cancer or who have been treated with tamoxifen. It also is approved for initial or second-line treatment of postmenopausal women with hormone-sensitive or advanced breast cancer. Letrozole is used to treat certain types of breast cancer in women who have already stopped menstruating. It is also used for women who have already had other cancer treatments.

 

Letrozole, an aromatase inhibitor, has been demonstrated to be effective as an ovulation induction and controlled ovarian hyperstimulation agent. However, dose administration has generally been limited to 5 days at 2.5 to 7.5 mg daily. We undertook a retrospective review of over 900 treatment cycles using letrozole in doses as high as 12.5 mg per day. Results indicate that such doses do indeed offer benefit to patients; in that there is increased follicular growth and a higher number of predicted ovulations with higher doses of the drug. However, increasing doses does not produce a detrimental effect upon endometrial thickness. High-dose letrozole may be of value in women who fail to respond adequately to lower doses. Furthermore, randomized trials are needed to determine whether high-dose letrozole might actually be optimal as a starting dose for certain treatment groups.

 

Letrozole can be used in patients working on getting pregnant with PCOS (or polycystic ovary syndrome) who have irregular or absent period. Letrozole can be used as an alternative in women who develop a thin uterine lining on clomiphene citrate. Unlike clomiphene citrate, with letrozole there is no blockage of estrogen receptors and the uterine lining and cervical mucus are not affected.

 

Letrozole is approved by the united states food and drug administration (fda) for the treatment of local or metastatic breast cancer that is hormone receptor positive or has an unknown receptor status in postmenopausal women. Letrozole is intended for use only by women who are no longer of childbearing age. Possible candidates must have already ceased to menstruate. It is often used in patients who have already undergone other cancer treatments, such as radiation, chemotherapy, and used other cancer drugs. This nonsteroidal aromatase inhibitor may help prevent any remaining cancer cells from spreading.

 

3. Applications:

 

You should check with your doctor immediately if any of these side effects occur when taking letrozole:

Less common:
Bone fracture
breast pain
chest pain
chills, fever, or flu-like symptoms
mental depression
shortness of breath
swelling of the feet or lower legs

 

 

The Recipe of Letrozole / Femara

 

 

Powder

 

Per 1 gram of Letrozole

 

Produces

 

Highest concentration made - 5 mg/ml

 

Requirements

 

1 gram of Letrozole powder;

1 beaker suitable for holding the volume of liquids;

19.9 ml of PEG 300;

179.1 ml of 190 Proof Grain Alcohol;

 

Use the following procedure

 

  • Place a sufficient amount of water in a pan and place on the stove
  • Remove from heat when the water reaches boiling temperature
  • Place the powder and the PEG in the beaker
  • Immerse the beaker in the pan of water so that the water is level with the top of the contents of the beaker gently swirl or stir the contents of the beaker until the solution is clear (reheat the water if necessary)
  • Remove the beaker from the water
  • Allow the PEG to cool down
  • Slowly add the 190 Proof Alcohol to the mixture
  • Chic stir until fully mixed.
  •  
  

 

About us:


we, Yihan Industrial Co., Ltd from china are specilized in steroids powder , semi-finished liquids , peptides , Sarm powder,HGH,HCG,Finished Liquid and other pharmaceutical materials for many years .

If you have any further questions or need a sample,Please do not hesitate to contact me.Thank you!

Juddy Email: sales01@yihanind.com
Phone(Whatsapp/ Wechat/Skype) +8613243765351
  snapchat/ wickr/instagram Juddy1966460 

 

 
 

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