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|Product Name:||Erlotinib Hydrochloride||Advantages:||Reship Policy|
|Suitable For:||Adult||Ship Way:||EMS,HKEMS,Fedex,DHL, HKPOST|
|Appearance:||White Powder||Grade:||High Build And Good Leveling,Pharmaceutcial Grade|
Pharma Raw Materials,
Erlotinib Hcl English name: Erlotinib hydrochloride
Erlotinib Hcl CAS Number: 183319-69-9
Erlotinib Hcl Molecular formula: C22H24ClN3O4
Erlotinib Hcl Molecular weight: 429.9
Erlotinib Hcl EINECS number:
Erlotinib Hcl Related Keywords: API; Molecular Targeted Antineoplastic; Heterocyclic Compounds; anti-neoplastic; Anti-cancer drugs; Heterocycles; Intermediates & Fine Chemicals; Pharmaceuticals; Research reagents; Anti-tumor;
Erlotinib Hcl Mol file: 183319-69-9.mol
Erlotinib Hcl Properties of erlotinib HCl
Erlotinib Hcl Melting point 223-225 ° C
Erlotinib Hcl Storage conditions -20 ° C Freezer
Erlotinib Hcl CAS database 183319-69-9 (CAS DataBase Reference)
Erlotinib hydrochloride is a drug used to treat non-small cell lung cancer, pancreatic cancer and several other types of cancer. Similar to gefitinib, erlotinib specifically targets the epidermal receptor (EGFR) tyrosine kinase. It binds in a reversible fashion to the adenosine triphosphate (ATP) binding site of the receptor. Erlotinib has recently been shown to be a potent inhibitor of JAK2V617F activity. JAK2V617F is a mutant of tyrosine kinase JAK2, is found in most patients with polycythemia vera (PV) and a substantial proportion of patients with idiopathic myelofibrosis or essential thrombocythemia. The study suggests that erlotinib may be used for treatment of JAK2V617F-positive PV and other myeloproliferative disorders.
Antitumor Drugs Erlotinib is a small molecule epidermal growth factor receptor tyrosine kinase reversible inhibitor, mainly used for local advanced or metastatic non-small cell lung cancer second or third line treatment and pancreatic cancer treatment.
Product Name:Erlotinib hydrochloride
Synonyms:ERLOTINIB HCL;ERLOTINIB HCL SALT;ERLOTINIB HCL SALT :TARCEVA;Erlotinib, Hydrochloride Salt;N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine, Hydrochloride Salt, OSI 774, Tarceva;N-(3-Ethynylphenyl)-6,7-bis-(2-methoxyethoxy)-quinazolin-4-amine;[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4yl]-(3-ethynyl-phenyl)-amine;Tarceva HydrochlorideSee E625000
Product Categories:API;Molecular Targeted Antineoplastic;Heterocyclic Compounds;anti-neoplastic;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Tarceva;Antineoplastic;Anti-cancer&immunity;Inhibitors
Erlotinib hydrochlorate is a small molecule tyrosine kinase inhibitor which acts reversibly on epidermal grow factor receptors, a hydrochloride of erlotinib, a molecular-targeted drug. The US Food and Drug Administration (FDA) has approved erlotinib (Tarceva) combined with gemcitabine as a first-line treatment for locally advanced and metastatic pancreatic cancer.
It is mainly used as a second- or third-line treatment for locally advanced or metstatic non-small cell lung cancer (NSCLC) and as a treatment for pancreatic cancer. It is used as a tyrosine inhibitor for NSCLC treatment.
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