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|Molecular Weight:||380.5613||Molecular Formula::||C23H40O4|
|Guarantee:||Support Re-Sending Police||HS Code:||552667889|
|Synonyms:||Cytotec; Sc-29333||Application:||A Progesterone Receptor Antagonist With Partial Agonist Activity. Abortifacient. Glutamate Uptake Inhibitor, AMPA Blocker|
Pharma Raw Materials,
Terminate Pregnancy Pharmaceutical Intermediates Prostaglandin Misoprostol CAS 59122-46-2
|Appearence||Pale Yellow Solid|
|Application||A progesterone receptor antagonist with partial agonist activity. Abortifacient.|
glutamate uptake inhibitor, AMPA blocker
Misoprostol is a medication used to start labor, induce abortions, prevent and treat stomach ulcers, and treat postpartum bleeding due to insufficient contraction of the uterus. For abortions it is used with mifepristone or methotrexate. It is a synthetic prostaglandin E1 (PGE1).
Common side effects include diarrhea and abdominal pain. It is pregnancy category X meaning that it is known to result in negative fetal outcomes if taken during pregnancy. Uterine rupture may occur.
It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. Misoprostol was invented and marketed by G.D. Searle & Company under the trade name Cytotec, but other trade names and generic formulations are available.
|Payment & Shipping Terms|
|Minimum Order Quantity||10gram||Payment Terms||Western union,Money gram,t/t|
|Packing||foil bag or tin|
|Standard||Enterprise Standard||Appearance||white powder|
|Use||Misoprostol is used for the prevention of NSAID-induced gastric ulcers. Misoprostol acts upon gastric parietal cells, inhibiting the secretion of gastric acid by G-protein coupled receptor-mediated inhibition of adenylate cyclase, which leads to decreased intracellular cyclic AMP levels and decreased proton pump activity at the apical surface of the parietal cell. Because other classes of drugs, especially H2-receptor antagonists and proton pump inhibitors, are more effective for the treatment of acute peptic ulcers, misoprostol is only indicated for use by people who are both taking NSAIDs and are at high risk for NSAID-induced ulcers, including the elderly and people with ulcer complications.|
Misoprostol is sometimes coprescribed with NSAIDs to prevent their common adverse effect of gastric ulceration.
Misoprostol is used either alone or in conjunction with an other medication (mifepristone or methotrexate) for medical abortions as an alternative to surgical abortion. Medical abortion has the advantage of being less invasive, and more autonomous, self-directed, and discreet. It is preferable to users because it feels more "natural," as the drugs induce a miscarriage. Misoprostol is also more easily accessible in places where abortion is illegal.The World Health Organization provides clear guidelines on the use, benefits and risks of misoprostol for abortions.
Misoprostol is most effective when it is used with methotrexate or mifepristone (RU-486). Misoprostol alone is less effective (typically 88% up to eight-weeks gestation).
Misoprostol has been shown to produce uterine contractions that may endanger pregnancy.
Other pharmacologic effects
Misoprostol does not produce clinically significant effects on serum levels of prolactin, gonadotropins, thyroid-stimulating hormone, thyroxine, cortisol, gastrointestinal hormones (somatostatin, gastrin, vasoactive intestinal polypeptide, and motilin), creatinine, or uric acid. Gastric emptying, immunologic competence, platelet aggregation, pulmonary function, or the cardiovascular system are not modified by recommended doses of misoprostol.
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4. High quality service : Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%, As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.