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Intermediate Raw Powder Dasatinib BMS-354825 For Anti -Tumor CAS 302962-49-8

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Intermediate Raw Powder Dasatinib BMS-354825 For Anti -Tumor CAS 302962-49-8

China Intermediate Raw Powder Dasatinib BMS-354825 For Anti -Tumor CAS 302962-49-8 supplier
Intermediate Raw Powder Dasatinib BMS-354825 For Anti -Tumor CAS 302962-49-8 supplier Intermediate Raw Powder Dasatinib BMS-354825 For Anti -Tumor CAS 302962-49-8 supplier

Large Image :  Intermediate Raw Powder Dasatinib BMS-354825 For Anti -Tumor CAS 302962-49-8

Product Details:

Place of Origin: China
Brand Name: YIHAN
Certification: GMP,USP,BP,ISO 9001
Model Number: Dasatinib powder

Payment & Shipping Terms:

Minimum Order Quantity: 10G
Price: USD0.1-2 +g
Packaging Details: Discreet Package or as Required.
Delivery Time: 3-5 work days
Payment Terms: MoneyGram,Paypal, T/T, Western Union
Supply Ability: 5000kg/Month
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Detailed Product Description
Product Name: Dasatinib Advantages: Reship Policy
Suitable For: Adult CAS: 302962-49-8
Type: Pharmaceutical Intermediate Appearance: White Powder
Grade: High Build And Good Leveling,Pharmaceutcial Grade
High Light:

Pharma Raw Materials

,

Medicine Intermediate

1. Basic Info

Product Name Dasatinib
CAS 302962-49-8
Purity 99%
Molecular Formula C22H28ClN7O3S
Molecular Weight 488.01
Molecular Structure Intermediate Raw Powder Dasatinib BMS-354825 For Anti -Tumor CAS 302962-49-8 0
Payment Method Western Union, Bank Transfer, MoneyGram, Bitcoin, Litecoin
 

 

 

2. Descriptions:

 

Dasatinib monohydrate is a pyrimidine and thiazole derived ANTINEOPLASTIC AGENT and PROTEIN KINASE INHIBITOR of BCR-ABL KINASE. It is used in the treatment of patients with CHRONIC MYELOID LEUKEMIA who are resistant or intolerant to IMATINIB.

 

 

Dasatinib is an oral dual BCR/ABL and Src family tyrosine kinase inhibitor approved for use in patients with chronic myelogenous leukemia (CML). The main targets of Dasatinib, are BCRABL, SRC, Ephrins and GFR.

 

For the treatment of adults with chronic, accelerated, or myeloid or lymphoid blast phase chronic myeloid leukemia with resistance or intolerance to prior therapy. Also indicated for the treatment of adults with Philadelphia chromosome-positive acute lymphoblastic leukemia with resistance or intolerance to prior therapy.

 

Dasatinib, previously known as BMS-354825, is a cancer drug produced by Bristol-Myers Squibb and sold under the trade name Sprycel. Dasatinib is an oral Bcr-Abl tyrosine kinase inhibitor (inhibits the "Philadelphia chromosome") and Src family tyrosine kinase inhibitor approved for first line use in patients with chronic myelogenous leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). It is being evaluated for use in numerous other cancers, including advanced prostate cancer.

 

 

3. detail

 

The COA of Gefitinib:

Product name  

Gefitinib

CAS No.  

184475-35-2

Outer Packing  

1kg/foil bag

Production date  

2017-2-25

Shelf life  

2 years

Standard adopted  

In-house standard

 

4. Applications:

 

Dasatinib, at nanomolar concentrations, inhibits the following kinases: BCR-ABL, SRC family (SRC, LCK, YES, FYN), c-KIT, EPHA2, and PDGFRβ. Based on modeling studies, dasatinib is predicted to bind to multiple conformations of the ABL kinase. In vitro, dasatinib was active in leukemic cell lines representing variants of imatinib mesylate sensitive and resistant disease. Dasatinib inhibited the growth of chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL) cell lines overexpressing BCR-ABL. Under the conditions of the assays, dasatinib was able to overcome imatinib resistance resulting from BCR-ABL kinase domain mutations, activation of alternate signaling pathways involving the SRC family kinases (LYN, HCK), and multi-drug resistance gene overexpression.

 

 

other product : 

 

Product Name Cas No
Erlotinib hydrochloride 183319-69-9
Octenidine Dihydrochloride 70775-75-6
Lapatinib Ditosylate 388082-77-7
Gefitinib 184475-35-2
Dasatinib 302962-49-8
Crizotinib 877399-52-5
Ibrutinib 936563-96-1
BIBW2992 DiMaleate 850140-73-7
Cabozantinib Malate 1140909-48-3
lenvatinib Mesylate 857890-39-2
Ceritinib (LDK378) 1032900-25-6
Cabozantinib 849217-68-1
lenvatinib 417716-92-8
Imatinib mesylate 220127-57-1

 

 

About us:

we, Yihan Industrial Co., Ltd from china are specilized in steroids powder , semi-finished liquids , peptides , Sarm powder,HGH,HCG,Finished Liquid and other pharmaceutical materials for many years .

If you have any further questions or need a sample,Please do not hesitate to contact me.Thank you!

Juddy Email: sales01@yihanind.com
Phone(Whatsapp/ Wechat/Skype) +8613243765351
 

 

 

 

 
 
 

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