CAS 81409-90-7 Pharmaceutical Intermediates Cabergoline Dostinex For Anti-B Cell Hematological Malignancies

CAS 81409-90-7 Pharmaceutical Intermediates Cabergoline Dostinex For Anti-B Cell Hematological Malignancies

Alias: Cabaser, Dostinex; Dostine, 6-Allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)ergoline-8-carboxamide
CAS: 81409-90-7
Molecular Formula: C26H37N5O2
Molecular Weight: 451.6
Melting Point: 102-104° C

Properties:
White powder. Soluble in ethyl alcohol, chloroform, and N, Ndimethylformamide (DMF); Slightly soluble in 0.1N hydrochloric acid; Very slightly soluble in n-hexane; And insoluble in water.

Description:
Pharmaceutical intermediates. This medication is used to treat high levels of prolactin hormone in your body. High levels of prolactin in women can cause symptoms such as unwanted breast milk and missed periods and can cause difficulty becoming pregnant. High levels of prolactin in men can cause symptoms such as enlarged breasts and decreased sexual ability/desire. Cabergoline is an ergot medication and works by blocking the release of prolactin from the pituitary gland.

fuction:

1. hyperprolactinemia
2. adjunctive therapy of prolactin-producing pituitary gland tumors (prolactinomas);
3. monotherapy of Parkinson's disease in the early phase;
4. combination therapy, together with levodopa and a decarboxylase inhibitor such as carbidopa, in progressive-phase Parkinson's disease;
5. in some countries also: ablactation and dysfunctions associated with hyperprolactinemia (amenorrhea, oligomenorrhea, anovulation, nonpuerperal mastitis and galactorrhea);
6. treatment of uterine fibroids.
7. adjunctive therapy of acromegaly, cabergoline has low efficacy in suppressing levels and is highly efficient in suppressing hyperprolactinemia that is present in 20-30% of acromegaly cases;
8.and prolactin are similar structurally and have similar effects in many target tissues, therefore targeting prolactin may help symptoms when hormone secretion can not be sufficiently controlled by other methods;
9. Cushing's disease - cabergoline may be used to lower ACTH levels and cause regression of ACTH producing pituitary adenomas;
10. other pituitary adenomas - cabergoline has demonstrated certain efficacy in controlling or reducing other kinds of pituitary adenomas, as well as silent or non-functional adenomas.

How to use cabergoline:
Use cabergoline as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Take cabergoline by mouth with or without food.
It may be helpful to mark on a calendar which days you are supposed to take cabergoline.
If you miss a dose of cabergoline, contact your doctor right away.
Ask your health care provider any questions you may have about how to use cabergoline.

Dosage
Parkinson's disease: Monotherapy: Initial dose should be 0.5 mg daily. The usual maintenance dose is 2 to 4 mg daily. Combination therapy: Usually 2 to 6 mg daily.
Tumors of the pituitary gland and other hyperprolactinemic conditions: Initially 0.5 mg per week, slowly titrated to 4.5 mg per week, if necessary.
Ablactation: According to specific treatment scheme.



CERTIFCATE OF ANALYSIS

Starage terms:Preserve in tight,light resistant containers at atemperature from+2ºCto+8ºC

Related products

Bodybuilding Steroid Powder/Raw Material Hormone Powder/ Enhances Muscle Steroid Powder:
Testosteron. (CAS: 58-22-0) Testosterone Enanthate (CAS: 315-37-7)
Testosterone Cypionate (CAS: 58-20-8) Testosterone Isocaproate (CAS: 15262-86-9)
Testosterone Decanoate (CAS: 5721-91-5) Testosterone Undecanoate (CAS: 5949-44-0)
Testosterone Propionate (CAS: 57-85-2)

Oxandrolon (Anava) (CAS: 53-39-4) Oxymetholon (Anadro) (CAS: 434-07-1)
Stanozolo (Winstro) (CAS: 10418-03-8) Metandieno...(Danabo) (CAS: 72-63-9

Trenbolone Enanthate(CAS: 472-61-5) Trenbolone Acetate (CAS: 10161-34-9)
Trenbolone Cyclohexylmethylcarbonate (CAS: 23454-33-3)
Methenolone Acetate (CAS: 434-05-9) Methenolone Enanthate (CAS: 303-42-4)

Nandrolon (CAS: 434-22-0) Nandrolone Decanoate(Deca-durabolin) (CAS: 360-70-3)
Nandrolone Cypionate (CAS: 601-63-8) Nandrolone Undecylate (CAS: 862-89-5)
Nandrolone Phenylpropionate (CAS: 62-90-8)

Boldenon (CAS: 846-48-0) Boldenone acetate (CAS: 2363-59-9)
Boldenone Cypionate (CAS: 106505-90-2) Boldenone Undecylenate(Equipoise) (CAS: 13103-34-9)


Male Enhancement /Sex Products:

Vardenafil (Levitr) (CAS: 224785-91-5) (CAS: 119356-77-3)

Weight Loss Powder:
Sibutramin Hydrochloride (CAS: 106650-56-0) Phentermin Hydrochloride(CAS: 1197-21-3)
L(-)-Carnitine (CAS: 541-15-1) Rimonabant (CAS: 158681-13-1)

Antineoplastic Powder:
Letrozol (CAS: 112809-51-5) Anastrozol (Arimidex) (CAS: 120511-73-1)
L-Triiodothyronine(T3) (CAS: 55-06-1) Trilostan (CAS: 13647-35-3)


Estrogen Hormone/Estrogen-blocking Powder:
Tamoxifen Citrate(Nolvadex) (CAS: 54965-24-1) Clomiphene Citrate(Clomid) (CAS: 50-41-9)
Progesterone (CAS: 57-83-0) Estradiol (CAS: 50-28-2)
Estradiol valerate (CAS: 979-32-8) Diethylstilbestrol (CAS: 56-53-1)
Hexestrol (CAS: 84-16-2)

Surface Anesthesia Powder:
Benzocaine (CAS: 94-09-7) Tetracaine Hydrochloride (CAS: 136-47-0)
Procaine Hydrochloride (CAS: 51-05-8) Lidocaine Hydrochloride (CAS: 6108-05-0)